Flowflex 4-in-1 RSV + Flu A/B + COVID-19 Home Tests
One nasal swab, one device, four answers in 15 minutes — distinguish RSV, influenza A, influenza B, and COVID-19 without a clinic visit.
Shop Flowflex Respiratory Home Tests
All products are FDA-cleared and ship same-day on orders placed by 3pm ET.
In short
The Flowflex Plus 4-in-1, made by ACON Laboratories, is an over-the-counter rapid antigen test that screens for four respiratory pathogens from a single self-collected nasal swab: respiratory syncytial virus (RSV), influenza A, influenza B, and SARS-CoV-2 (COVID-19). Because winter respiratory illnesses present with overlapping symptoms, a multiplex test that separates them in one step helps people and frontline staff make faster decisions about isolation, antiviral timing, and when to seek care. Results develop in about 15 minutes and are read directly from the device. This is a respiratory infection test, not a drug-of-abuse screen, and it's designed for simple, instructions-only use at home, in schools, in workplaces, and in pharmacies. We stock it both as a single retail pack and as a 48-count bulk case for organizations that buy ahead of respiratory season.
Why a 4-in-1 respiratory test?
RSV, influenza, and COVID-19 look almost identical at the bedside — fever, cough, congestion, fatigue — yet they call for different responses. A single multiplex test that distinguishes all four targets in one run removes the guesswork that single-disease tests leave behind, so a person knows within minutes whether they're dealing with flu (where early antivirals matter), COVID-19 (where isolation and treatment guidance differ), or RSV (which carries particular risk for infants and older adults).
For organizations, the operational case is about throughput and clarity. Instead of stocking and running three separate tests, or sending symptomatic people away to a clinic, a 4-in-1 lets a school nurse, an HR team, or a pharmacy counter resolve the most common winter question — 'what do I have?' — in a single, inexpensive step. That speeds isolation decisions during a surge and reduces the number of people who stay home uncertain or come in sick.
The Flowflex line, from ACON Laboratories, is widely recognized for straightforward, reliable rapid antigen testing, and the Plus 4-in-1 extends that simplicity to a combined panel. The workflow is the familiar self-collected nasal swab — no deep nasopharyngeal sampling, no separate analyzer — with a 15-minute read. For bulk buyers, that ease of use translates into fewer user errors and less hand-holding across a large group of untrained users. We carry the product under its own brand and packaging — it is not rebranded — so what you stock is the recognizable Flowflex kit.
Packaging flexibility is part of why the product fits both shelves and stockrooms. The single pack suits a household or a retail peg, while the 48-count bulk case is built for a school district, clinic, or employer that wants a season's worth on hand at the best per-test price. Both contain the same device and instructions; the only difference is how many you buy at once.
Keep in mind what the test is and isn't. It's a screening tool for active infection that performs best when someone is symptomatic and viral loads are high; a negative result early in an illness doesn't fully rule out infection, and clinical judgment or a follow-up test still matters. It's also entirely separate from drug-of-abuse testing — it belongs in your respiratory-season and employee-wellness toolkit, not your screening program.
4-in-1 vs. single-disease tests
One multiplex swab separates RSV, Flu A, Flu B, and COVID in a single step — no stocking or running three different tests.
Antigen vs. lab PCR
Rapid antigen gives an answer in 15 minutes at the point of need; PCR is more sensitive but requires a lab and a turnaround wait.
What sets these apart
Four pathogens, one swab
Detects RSV, influenza A, influenza B, and SARS-CoV-2 from a single self-collected nasal sample.
Built for respiratory season
Separates overlapping winter illnesses so isolation, antiviral, and care decisions can be made quickly.
Results in ~15 minutes
Read directly from the device — no analyzer, no lab, no app required.
OTC, instructions-only
Designed for simple at-home use by untrained users, which keeps error rates low across large groups.
Single packs or 48-count bulk
Stock single retail packs for shelves and households, or a 48-count case for schools, clinics, and employers.
FDA-authorized for home use
Authorized for over-the-counter use; see the package insert for the exact authorization and intended-use details.
Recommended for these industries
The Flowflex 4-in-1 fits any setting that needs fast, clear answers during respiratory season. Common buyers include:
Schools & Universities
Resolve symptomatic students quickly during flu and RSV season to guide isolation and return-to-class.
Explore →Workplace HR
Employee-wellness and return-to-work decisions without sending symptomatic staff to a clinic.
Explore →Hospitals & Medical
Triage and staff-screening support where a fast multiplex answer speeds isolation decisions.
Explore →Staffing Agencies
Keep placed workers and shared worksites healthy with on-hand rapid respiratory testing.
Explore →Bulk & wholesale pricing
The Flowflex 4-in-1 is priced in automatic volume tiers, so the per-test cost falls as your order grows — useful when an organization stocks ahead of respiratory season. The 48-count bulk case is the simplest way to reach a better tier in a single purchase, while single packs suit retail pegs and households. Pricing is quoted per individual test, and the cart always applies the lowest tier your quantity qualifies for, with no code to enter. A typical schedule runs four tiers: a starter tier for smaller orders, a mid tier, a program tier, and a contract tier for the largest standing buyers, with the unit price stepping down at each threshold. Approved wholesale accounts can add negotiated per-item rates and are always charged the lower of the tier price or their account rate. Because demand is seasonal, many schools, clinics, and employers place a single large pre-season order to lock in the best tier and avoid mid-surge shortages — request a bulk quote and we'll size pricing and supply to your expected season.
Compliance & certifications
The Flowflex Plus 4-in-1 is a respiratory antigen test authorized by the FDA for over-the-counter, at-home use. Its regulatory pathway and intended use differ from the drug-of-abuse devices elsewhere in our catalog — it is not CLIA-waived in the drug-testing sense, and it should never be used or marketed as a drug screen. Always rely on the package insert for the precise authorization, claims, and instructions for use, and follow the manufacturer's storage and handling guidance.
Like all rapid antigen tests, it detects active infection most reliably when viral load is high, which usually means when symptoms are present. A negative result does not definitively rule out infection — especially very early in illness — and clinical correlation or repeat or PCR testing may be warranted. A positive result indicates likely infection with the corresponding pathogen and should guide isolation and care decisions per current public-health guidance.
Because this is a self-administered consumer test, there is no chain-of-custody or laboratory-confirmation workflow attached to it the way there is with employment drug screening. Organizations deploying it at scale should provide the manufacturer's instructions to users and a simple plan for what to do with positive results.
For detection of respiratory pathogens only — not a drug-of-abuse test. A negative result does not rule out infection; follow current public-health guidance and consult a healthcare provider as needed.
Frequently asked questions
What does the Flowflex 4-in-1 actually test for?+
It screens for four respiratory targets from one nasal swab: respiratory syncytial virus (RSV), influenza A, influenza B, and SARS-CoV-2 (the virus that causes COVID-19). Each target reads on the device so you can tell which infection — if any — is present, rather than just getting a single positive or negative.
When should I take the test for the most reliable result?+
Rapid antigen tests work best once symptoms have started, because that's when viral load is usually high enough to detect. If you test very early — within the first day of symptoms or right after an exposure — a negative result is less reliable, so repeat the test after a day or two. Read the result inside the time window in the package insert: too early can miss a developing line, and too late can produce an invalid result.
Is this a drug test?+
No. The Flowflex 4-in-1 is a respiratory infection test for RSV, flu, and COVID-19. It has no relationship to drug-of-abuse screening and cannot detect any drugs. It lives in this catalog as a workplace, school, and pharmacy health product, separate from our drug-testing lines.
How accurate is a rapid antigen test like this?+
Rapid antigen tests are most accurate when a person is symptomatic and viral load is high; in that window they correlate well with lab testing. Sensitivity is lower very early in an infection or when someone is asymptomatic, so a negative early result doesn't fully rule out infection. When in doubt, repeat the test after a day or two or follow up with a PCR test and clinical advice.
What should I do after a positive result?+
A positive line indicates likely infection with that pathogen. Follow current public-health guidance on isolation and masking, and contact a healthcare provider — early antivirals can help for influenza and COVID-19, and RSV warrants extra caution for infants and older adults. For organizations, have a simple written plan so staff know what to do when someone tests positive on-site.
What's the difference between the single pack and the 48-count case?+
Nothing about the test itself — both contain the same device and instructions. The single pack is sized for a household or a retail shelf, while the 48-count bulk case is meant for schools, clinics, and employers stocking a season's supply at the best per-test price. Choose the pack size that matches how many tests you expect to use.
How should the kits be stored?+
Store kits at the temperature range printed on the box, away from direct sunlight and freezing, and let cold stock reach room temperature before use. Don't open a pouch until you're ready to test, and don't use any kit past its expiration date. Follow the package insert for full storage and handling details.
Stock up before respiratory season.
Order single packs or a 48-count case, or request a bulk quote sized to your expected demand.
Explore other categories
SpermCheck Home Fertility Tests
Private, lab-free answers to two of men's most common questions — 'is my sperm count normal?' and 'did my vasectomy work?' — in the comfort of home.
View →Drug Test Cups
All-in-one integrated urine cups that collect, test, and read in a single sealed device — built for high-volume programs that can't afford a recollect.
View →Drug Test Dip Cards
Compact dip cards that deliver the same lab-grade screening chemistry as a cup at a fraction of the cost per test — ideal when you screen often and watch every dollar.
View →DNA Tests
At-home paternity and relationship DNA testing.
View →